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 Research on Clinical Depression

Research

Clinical Depression is a serious and common disorder of mood that is pervasive, intense and attacks the mind of the body at the same time. Depression can result in a serious disturbance of work, social and bodily functioning. Unlike grief or passing sadness, depression usually does not respond to a chance in circumstances(for example, good news) nor does it dissipate with time (in contrast to the grief over the death of a loved one). Depression can last for months or years if left untreated, resulting in disruption of relationship and productivity, disability or death.

Current theories indicate that clinical depression may be associated with an imbalanced of chemicals in the brain that carry communications between nerve cells that control mood and other bodily systems that are disturbed in depression, such as sleep and appetite. Factors contributing to vulnerability or the timing of depression also include life experience such as severe stress or loss, other medical illnesses, and certain personality traits and genetic factors. Sometimes, depression can appear without any apparent cause.

In most people, depression can be treated successfully, either with medication or psychotherapy, or a combination of the two. Antidepressant medications affect brain chemistry, and after several weeks can yield to important and sustained relief from depressive symptoms. Newer medications have greatly improved safety and tolerability. Antidepressant are not habit-forming and may be useful for long-term prevention of recurrences of depressive episodes or against chronic depression.


How does depression differ from the blues?

Depression The Blues
Essential Distinction An Illness Abnormal reaction to life situations
Symptoms Multiple: moods, thoughts,
bodily functions
Single: moods
Duration Persists Temporary
Suicide Potential Can result in suicide Rarely produces suicidal thoughts
Treatment Requires specific medical/ psychiatric
treatment
Requires a good listener and/or time to heal

Depression is a whole body illness involving physical symptoms, moods, and thoughts. It affects the way you eat and sleep, the way you feel about yourself, and the way you think about things. A depressive disorder is not a passing blue mood. It is not a sign of personal weakness or a condition that can be willed or wished away. People with a depressive illness cannot merely "pull themselves together" and get better. Without treatment, symptoms can last for months or years. This slide illustrates the difference between depression and the blues.

Who suffers from Depression?
Depression affects over 17 million Americans each year
Less than 1/2 of the people suffering from depression seek treatment.
1 of every 5 adults may experience a depression at some point during his her life.
Twice as many woman as men experiencing depression.

Signs and Symptoms of Depression
Depressed mood
Diminished interest or pleasure in activities.
Significant change in appetite and/or weight.
Sleep disturbance.
Restlessness or sluggishness.
Fatigue or loss of energy.
Feelings of worthlessness.
Thoughts of death or suicide.


Risk Factors
Some people are more at risk to experience a depressive episode than others. The main factors for depression are prior depressive episodes, family history of depression, and postpartum state.


Types of Depression

Major depression (unipolar) is the most common type of depression and is characterized by a cluster of at least five of the nine symptoms we discussed earlier. There are several levels of severity and impairment in major depression.


Dysthymia
, the second most common type, is a milder form of depression with symptoms lasting two years or more. Due to its duration, dysthymia can cause serious impairment. Because people with dysthymia may have only two or three of the symptoms associated with major depression, the seriousness of the diagnosis is often overlooked, and treatment is not purchased.


Bipolar depression
has a strong family linkage and exist equally in men and women.
It is the depressive phase of manic-depressive illness, in which there are both highs and lows. In general, the symptoms of bipolar depression are similar to those of major depression, with certain variations such as excessive slee and increase in appetite. The treatment of bipolar depression differs from that om major depression in that bipolar patients often require mood stabilizing medication in addition to antidepressant medication.


Seasonal Affective Disorder (SAD) i
s a type of depression that follows a seasonal rhythm, with symtoms occuring in the winter months and diminishing in the spring and summer. current research indicates that the absense of sunlight triggers a biochemical reaction that may cause symptoms such as loss of energy, decreased activity, sadness, excessive eating and sleeping. Eighty-three percent of those who suffer from this illness are women. Children are also vulnerable.
It is important not to confuse Seasonal Disorder with "holiday blues" which many feel as the result of increased stress during the holiday season. The most common treatment for Seasonal Affective Disorder is light therapy, exposure to intense light for a period of time each day. Medication and psychotherapy are also effective.

Co-Occuring Depression
People who suffer from a medical illness such as cancer, heart disease or stroke also may suffer from depression. when this happens, health professionals say that depression is co-occuring, or "comorbid" with the other illness.

Unfortunately, co-occuring depression often goes unrecognized, undiagnosed therefore, untreated. Since some symptoms of depression are identical to those present in other medical disorders, people often assume they are suffering only from their primary medical condition and not also

Suicide
People who suffer from a medical illness such as cancer, heart disease or stroke also may suffer from depression. when this happens, health professionals say that depression is co-occuring, or "comorbid" with the other illness.

Unfortunately, co-occurring depression often goes unrecognized, undiagnosed therefore, un



Support Groups

ADA Institute, National Depressive and Manic-Depressive Association and the National Alliance for the Mentally Ill offer an opportunity for people who are depressed as well as their families to gain emotional support, learn about depression and access the mental health system. Such groups offer a chance to interact with people who have suffered from depression and found ways to cope with it more effectively and overcome it.




 
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